Hi Michael from a fellow 1a on Harvoni. From what I have read, we GT1as can be more inclined to be in the slow lane reaching UND.
I am getting in week 10 the Harvoni fatigue currently. For me, the first few weeks on tx I had amazing energy, felt so much better and had a 'spring in my step' - I felt great! Then I managed to pick up some bug and get a chest infection / sinusitis in month two, so this really slowed me down. Month three I have improved, the sinusitis dragged on for weeks. It's hard to distinguish what was the bug and what is the sx. I am bright in the morning, but in the evening, I get very tired and can suddenly be overwhelmed with tiredness. I can literally 'pass out' in a matter of seconds. It is almost like an anesthetic effect it's that quick! a novel experience for me as I have always taken a while to get to sleep previously. I wake up in the night with reading glasses still on, lights and TV on etc
These are powerful medicines and it would be strange if we did not feel some sx like this after taking them for a while. Maybe it's the body's reaction, making us rest so the meds can do their stuff. Really, there is little in the way of data as yet as these meds are still very new. It makes sense that a longer tx will cause a few more sx too.
Well done for getting this far, I will be extending to a longer treatment period too, got to make sure we do everything we can to rid ourselves of this, it is also a drain on our mental energy as well as physical, no wonder we get tired. My very best wishes for every success, looking good for you now as UND some weeks back
ps At what stage did you add the Riba?
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC