Displaying items by tag: nmr

Wednesday, 08 July 2015 16:40

Sofosbuvir Reference NMR Comparison

Today we compared a new batch of Sofosbuvir and Ledipasvir to our reference sample data and found it consistent.

It's reassuring to see the consistency.

Published in Blogs
Wednesday, 10 June 2015 16:40

Sofosbuvir Ledipasvir NMR and Mass Spec

We were quite excited to see the first shipment of Chinese sourced Sofosbuvir and Ledipasvir. A white powder and and off white powder, but what would the NMR show? Here's the NMR for Sofosbuvir which is right on the money.

Ledipasvir: mass [M+H] + 889.4195 ( < 2 ppm error)

  • molecular formula - C49H54F2N8O6

Sofosbuvir: mass [M+H] + 530.1699 ( < 0.2 ppm error)

  • molecular formula - C22H29FN3O9P
Published in Blogs

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